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Dengue Virus Serotype 2 Blocks Extracellular Signal-Regulated Kinase and Nuclear Factor-κB Activation to Downregulate Cytokine Production
BACKGROUND: Dengue virus (DENV) infection is the most common mosquito-borne viral disease threatening human health around the world. Type I interferon (IFN) and cytokine production are crucial in the innate immune system. We previously reported that DENV serotype 2 (DENV-2) induced low levels of int...
Autores principales: | Chang, Tsung-Hsien, Chen, Siang-Ru, Yu, Chia-Yi, Lin, You-Sheng, Chen, Yao-Shen, Kubota, Toru, Matsuoka, Mayumi, Lin, Yi-Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425550/ https://www.ncbi.nlm.nih.gov/pubmed/22927911 http://dx.doi.org/10.1371/journal.pone.0041635 |
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