Yeast two-hybrid analysis of a human trabecular meshwork cDNA library identified EFEMP2 as a novel PITX2 interacting protein

PURPOSE: Mutations in the homeobox transcription factor paired-like homeodomain transcription factor 2 (PITX2) cause Axenfeld–Reiger syndrome (ARS), which is associated with anterior segment dysgenesis (ASD) and glaucoma. To understand ARS pathogenesis, it is essential to know the normal functions o...

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Detalles Bibliográficos
Autores principales: Acharya, Moulinath, Sharp, Michael W., Mirzayans, Farideh, Footz, Tim, Huang, LiJia, Birdi, Chanchal, Walter, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425575/
https://www.ncbi.nlm.nih.gov/pubmed/22919265

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