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Perlecan and the Blood-Brain Barrier: Beneficial Proteolysis?
The cerebral microvasculature is important for maintaining brain homeostasis. This is achieved via the blood-brain barrier (BBB), composed of endothelial cells with specialized tight junctions, astrocytes, and a basement membrane (BM). Prominent components of the BM extracellular matrix (ECM) includ...
Autores principales: | Roberts, Jill, Kahle, Michael P., Bix, Gregory J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425914/ https://www.ncbi.nlm.nih.gov/pubmed/22936915 http://dx.doi.org/10.3389/fphar.2012.00155 |
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