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Single-visit approach of cervical cancer screening: See and Treat in Indonesia
BACKGROUND: We performed a cross-sectional study in Indonesia to evaluate the performance of a single-visit approach of cervical cancer screening, using visual inspection with acetic acid (VIA), histology and cryotherapy in low-resource settings. METHODS: Women having limited access to health-care f...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425980/ https://www.ncbi.nlm.nih.gov/pubmed/22850550 http://dx.doi.org/10.1038/bjc.2012.334 |
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author | Vet, J N I Kooijman, J L Henderson, F C Aziz, F M Purwoto, G Susanto, H Surya, I G D Budiningsih, S Cornain, S Fleuren, G J Trimbos, J B Peters, A A W |
author_facet | Vet, J N I Kooijman, J L Henderson, F C Aziz, F M Purwoto, G Susanto, H Surya, I G D Budiningsih, S Cornain, S Fleuren, G J Trimbos, J B Peters, A A W |
author_sort | Vet, J N I |
collection | PubMed |
description | BACKGROUND: We performed a cross-sectional study in Indonesia to evaluate the performance of a single-visit approach of cervical cancer screening, using visual inspection with acetic acid (VIA), histology and cryotherapy in low-resource settings. METHODS: Women having limited access to health-care facilities were screened by trained doctors using VIA. If the test was positive, biopsies were taken and when eligible, women were directly treated with cryotherapy. Follow-up was performed with VIA and cytology after 6 months. When cervical cancer was suspected or diagnosed, women were referred. The positivity rate, positive predictive value (PPV) and approximate specificity of the VIA test were calculated. The detection rate for cervical lesions was given. RESULTS: Screening results were completed in 22 040 women, of whom 92.7% had never been screened. Visual inspection with acetic acid was positive in 4.4%. The PPV of VIA to detect CIN I or greater and CIN II or greater was 58.7% and 29.7%, respectively. The approximate specificity was 98.1%, and the detection rate for CIN I or greater was 2.6%. CONCLUSION: The single-visit approach cervical cancer screening performed well, showing See and Treat is a promising way to reduce cervical cancer in Indonesia. |
format | Online Article Text |
id | pubmed-3425980 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-34259802013-08-21 Single-visit approach of cervical cancer screening: See and Treat in Indonesia Vet, J N I Kooijman, J L Henderson, F C Aziz, F M Purwoto, G Susanto, H Surya, I G D Budiningsih, S Cornain, S Fleuren, G J Trimbos, J B Peters, A A W Br J Cancer Clinical Study BACKGROUND: We performed a cross-sectional study in Indonesia to evaluate the performance of a single-visit approach of cervical cancer screening, using visual inspection with acetic acid (VIA), histology and cryotherapy in low-resource settings. METHODS: Women having limited access to health-care facilities were screened by trained doctors using VIA. If the test was positive, biopsies were taken and when eligible, women were directly treated with cryotherapy. Follow-up was performed with VIA and cytology after 6 months. When cervical cancer was suspected or diagnosed, women were referred. The positivity rate, positive predictive value (PPV) and approximate specificity of the VIA test were calculated. The detection rate for cervical lesions was given. RESULTS: Screening results were completed in 22 040 women, of whom 92.7% had never been screened. Visual inspection with acetic acid was positive in 4.4%. The PPV of VIA to detect CIN I or greater and CIN II or greater was 58.7% and 29.7%, respectively. The approximate specificity was 98.1%, and the detection rate for CIN I or greater was 2.6%. CONCLUSION: The single-visit approach cervical cancer screening performed well, showing See and Treat is a promising way to reduce cervical cancer in Indonesia. Nature Publishing Group 2012-08-21 2012-07-31 /pmc/articles/PMC3425980/ /pubmed/22850550 http://dx.doi.org/10.1038/bjc.2012.334 Text en Copyright © 2012 Cancer Research UK https://creativecommons.org/licenses/by-nc-sa/3.0/From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ |
spellingShingle | Clinical Study Vet, J N I Kooijman, J L Henderson, F C Aziz, F M Purwoto, G Susanto, H Surya, I G D Budiningsih, S Cornain, S Fleuren, G J Trimbos, J B Peters, A A W Single-visit approach of cervical cancer screening: See and Treat in Indonesia |
title | Single-visit approach of cervical cancer screening: See and Treat in Indonesia |
title_full | Single-visit approach of cervical cancer screening: See and Treat in Indonesia |
title_fullStr | Single-visit approach of cervical cancer screening: See and Treat in Indonesia |
title_full_unstemmed | Single-visit approach of cervical cancer screening: See and Treat in Indonesia |
title_short | Single-visit approach of cervical cancer screening: See and Treat in Indonesia |
title_sort | single-visit approach of cervical cancer screening: see and treat in indonesia |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425980/ https://www.ncbi.nlm.nih.gov/pubmed/22850550 http://dx.doi.org/10.1038/bjc.2012.334 |
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