Cargando…

Single-visit approach of cervical cancer screening: See and Treat in Indonesia

BACKGROUND: We performed a cross-sectional study in Indonesia to evaluate the performance of a single-visit approach of cervical cancer screening, using visual inspection with acetic acid (VIA), histology and cryotherapy in low-resource settings. METHODS: Women having limited access to health-care f...

Descripción completa

Detalles Bibliográficos
Autores principales: Vet, J N I, Kooijman, J L, Henderson, F C, Aziz, F M, Purwoto, G, Susanto, H, Surya, I G D, Budiningsih, S, Cornain, S, Fleuren, G J, Trimbos, J B, Peters, A A W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425980/
https://www.ncbi.nlm.nih.gov/pubmed/22850550
http://dx.doi.org/10.1038/bjc.2012.334
_version_ 1782241441993457664
author Vet, J N I
Kooijman, J L
Henderson, F C
Aziz, F M
Purwoto, G
Susanto, H
Surya, I G D
Budiningsih, S
Cornain, S
Fleuren, G J
Trimbos, J B
Peters, A A W
author_facet Vet, J N I
Kooijman, J L
Henderson, F C
Aziz, F M
Purwoto, G
Susanto, H
Surya, I G D
Budiningsih, S
Cornain, S
Fleuren, G J
Trimbos, J B
Peters, A A W
author_sort Vet, J N I
collection PubMed
description BACKGROUND: We performed a cross-sectional study in Indonesia to evaluate the performance of a single-visit approach of cervical cancer screening, using visual inspection with acetic acid (VIA), histology and cryotherapy in low-resource settings. METHODS: Women having limited access to health-care facilities were screened by trained doctors using VIA. If the test was positive, biopsies were taken and when eligible, women were directly treated with cryotherapy. Follow-up was performed with VIA and cytology after 6 months. When cervical cancer was suspected or diagnosed, women were referred. The positivity rate, positive predictive value (PPV) and approximate specificity of the VIA test were calculated. The detection rate for cervical lesions was given. RESULTS: Screening results were completed in 22 040 women, of whom 92.7% had never been screened. Visual inspection with acetic acid was positive in 4.4%. The PPV of VIA to detect CIN I or greater and CIN II or greater was 58.7% and 29.7%, respectively. The approximate specificity was 98.1%, and the detection rate for CIN I or greater was 2.6%. CONCLUSION: The single-visit approach cervical cancer screening performed well, showing See and Treat is a promising way to reduce cervical cancer in Indonesia.
format Online
Article
Text
id pubmed-3425980
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-34259802013-08-21 Single-visit approach of cervical cancer screening: See and Treat in Indonesia Vet, J N I Kooijman, J L Henderson, F C Aziz, F M Purwoto, G Susanto, H Surya, I G D Budiningsih, S Cornain, S Fleuren, G J Trimbos, J B Peters, A A W Br J Cancer Clinical Study BACKGROUND: We performed a cross-sectional study in Indonesia to evaluate the performance of a single-visit approach of cervical cancer screening, using visual inspection with acetic acid (VIA), histology and cryotherapy in low-resource settings. METHODS: Women having limited access to health-care facilities were screened by trained doctors using VIA. If the test was positive, biopsies were taken and when eligible, women were directly treated with cryotherapy. Follow-up was performed with VIA and cytology after 6 months. When cervical cancer was suspected or diagnosed, women were referred. The positivity rate, positive predictive value (PPV) and approximate specificity of the VIA test were calculated. The detection rate for cervical lesions was given. RESULTS: Screening results were completed in 22 040 women, of whom 92.7% had never been screened. Visual inspection with acetic acid was positive in 4.4%. The PPV of VIA to detect CIN I or greater and CIN II or greater was 58.7% and 29.7%, respectively. The approximate specificity was 98.1%, and the detection rate for CIN I or greater was 2.6%. CONCLUSION: The single-visit approach cervical cancer screening performed well, showing See and Treat is a promising way to reduce cervical cancer in Indonesia. Nature Publishing Group 2012-08-21 2012-07-31 /pmc/articles/PMC3425980/ /pubmed/22850550 http://dx.doi.org/10.1038/bjc.2012.334 Text en Copyright © 2012 Cancer Research UK https://creativecommons.org/licenses/by-nc-sa/3.0/From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Clinical Study
Vet, J N I
Kooijman, J L
Henderson, F C
Aziz, F M
Purwoto, G
Susanto, H
Surya, I G D
Budiningsih, S
Cornain, S
Fleuren, G J
Trimbos, J B
Peters, A A W
Single-visit approach of cervical cancer screening: See and Treat in Indonesia
title Single-visit approach of cervical cancer screening: See and Treat in Indonesia
title_full Single-visit approach of cervical cancer screening: See and Treat in Indonesia
title_fullStr Single-visit approach of cervical cancer screening: See and Treat in Indonesia
title_full_unstemmed Single-visit approach of cervical cancer screening: See and Treat in Indonesia
title_short Single-visit approach of cervical cancer screening: See and Treat in Indonesia
title_sort single-visit approach of cervical cancer screening: see and treat in indonesia
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425980/
https://www.ncbi.nlm.nih.gov/pubmed/22850550
http://dx.doi.org/10.1038/bjc.2012.334
work_keys_str_mv AT vetjni singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT kooijmanjl singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT hendersonfc singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT azizfm singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT purwotog singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT susantoh singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT suryaigd singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT budiningsihs singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT cornains singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT fleurengj singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT trimbosjb singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia
AT petersaaw singlevisitapproachofcervicalcancerscreeningseeandtreatinindonesia