Cargando…

Genetic and Biochemical Alterations in Non-Small Cell Lung Cancer

Despite significant advances in the detection and treatment of lung cancer, it causes the highest number of cancer-related mortality. Recent advances in the detection of genetic alterations in patient samples along with physiologically relevant animal models has yielded a new understanding of the mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Johnson, Jackie L., Pillai, Smitha, Chellappan, Srikumar P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426175/ https://www.ncbi.nlm.nih.gov/pubmed/22928112 http://dx.doi.org/10.1155/2012/940405

Ejemplares similares

Nicotinic Acetylcholine Receptor Signaling in Tumor Growth and Metastasis
por: Singh, Sandeep, et al.
Publicado: (2011)

Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer
por: Schaal, Courtney M, et al.
Publicado: (2018)

Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis
por: Pillai, Smitha, et al.
Publicado: (2015)

Nicotine-Mediated Regulation of Nicotinic Acetylcholine Receptors in Non-Small Cell Lung Adenocarcinoma by E2F1 and STAT1 Transcription Factors
por: Schaal, Courtney, et al.
Publicado: (2016)

Nicotinic acetylcholine receptors induce c-Kit ligand/Stem Cell Factor and promote stemness in an ARRB1/ β-arrestin-1 dependent manner in NSCLC
por: Perumal, Deepak, et al.
Publicado: (2014)

βArrestin-1 and Mcl-1 Modulate Self-Renewal Growth of Cancer Stem-Like Side-Population Cells in Non-Small Cell Lung Cancer
por: Singh, Sandeep, et al.
Publicado: (2013)

Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer()
por: Bora-Singhal, Namrata, et al.
Publicado: (2015)

Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner
por: Nair, Sajitha, et al.
Publicado: (2014)

EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer
por: Singh, Sandeep, et al.
Publicado: (2012)

Alterations in genes other than EGFR/ALK/ROS1 in non-small cell lung cancer: trials and treatment options
por: Desai, Arpita, et al.
Publicado: (2016)

Smoking Cessation after Cancer Diagnosis and Enhanced Therapy Response: Mechanisms and Significance
por: Chellappan, Srikumar
Publicado: (2022)

Characterization of genetic alterations in brain metastases from non‐small cell lung cancer
por: Liao, Li, et al.
Publicado: (2018)

Oncogenic Genetic Alterations in Non-Small-Cell Lung Cancer (NSCLC) in Southwestern China
por: Ma, Yuhui, et al.
Publicado: (2020)

Molecular Epidemiology of the Main Druggable Genetic Alterations in Non-Small Cell Lung Cancer
por: Fois, Sara S., et al.
Publicado: (2021)

Alterations of lung microbiota in patients with non-small cell lung cancer
por: Zeng, Wen, et al.
Publicado: (2022)

The Role of nAChR and Calcium Signaling in Pancreatic Cancer Initiation and Progression
por: Schaal, Courtney, et al.
Publicado: (2015)

Nicotine Promotes Tumor Growth and Metastasis in Mouse Models of Lung Cancer
por: Davis, Rebecca, et al.
Publicado: (2009)

Genetic Alteration and Their Significance on Clinical Events in Small Cell Lung Cancer
por: Jiao, Shuyue, et al.
Publicado: (2022)

BCKDK alters the metabolism of non-small cell lung cancer
por: Wang, Yanhui, et al.
Publicado: (2021)

Alterations of immune response of non-small cell lung cancer with Azacytidine
por: Wrangle, John, et al.
Publicado: (2013)

Altered expression of ACOX2 in non-small cell lung cancer
por: Sui, Jane S. Y., et al.
Publicado: (2022)

Inhibitors Targeting CDK9 Show High Efficacy against Osimertinib and AMG510 Resistant Lung Adenocarcinoma Cells
por: Padmanabhan, Jaya, et al.
Publicado: (2021)

Smoking alters the evolutionary trajectory of non-small cell lung cancer
por: Yu, Xiao-Jun, et al.
Publicado: (2019)

Consensus for HER2 alterations testing in non-small-cell lung cancer
por: Ren, S., et al.
Publicado: (2022)

Cytotoxic mechanisms of berberine-phytantriol liquid crystalline nanoparticles against non-small-cell lung cancer
por: Paudel, Keshav Raj, et al.
Publicado: (2023)

Mammalian Lysine Histone Demethylase KDM2A Regulates E2F1-Mediated Gene Transcription in Breast Cancer Cells
por: Rizwani, Wasia, et al.
Publicado: (2014)

High Frequency of Genetic Alterations in Non-small Cell Lung Cancer Detected by Multi-target Fluorescence In Situ Hybridization
por: Kang, Ji Un, et al.
Publicado: (2007)

Variation in targetable genomic alterations in non-small cell lung cancer by genetic ancestry, sex, smoking history, and histology
por: Adib, Elio, et al.
Publicado: (2022)

Real-World Outcomes of Immunotherapy in Second- or Later-Line Non-Small Cell Lung Cancer with Actionable Genetic Alterations
por: Jun, Soojin, et al.
Publicado: (2023)

Optimal Therapy for Advanced Non-Small Cell Lung Cancer Without Driver Alterations
por: Pacheco, Jose, et al.
Publicado: (2021)

Classification of Non-Small Cell Lung Cancer Based on Copy Number Alterations
por: Li, Bi-Qing, et al.
Publicado: (2014)

Alterations in body composition in Indian patients with non-small cell lung cancer
por: Mohan, Anant, et al.
Publicado: (2019)

Altered phosphatidylcholines expression in sputum for diagnosis of non-small cell lung cancer
por: Zhang, Jianyong, et al.
Publicado: (2016)

Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling
por: Woods, Neha, et al.
Publicado: (2015)

Landscape and clinical impact of metabolic alterations in non-squamous non-small cell lung cancer
por: Ivanina Foureau, Anna V., et al.
Publicado: (2022)

Genetic polymorphisms and non-small-cell lung cancer: future paradigms
por: de Mello, Ramon Andrade Bezerra
Publicado: (2014)

Endoplasmic reticulum Ca(2+)-homeostasis is altered in small and non-small cell lung cancer cell lines
por: Bergner, Albrecht, et al.
Publicado: (2009)

Epigenetic alterations are associated with tumor mutation burden in non-small cell lung cancer
por: Cai, Liangliang, et al.
Publicado: (2019)

Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL
por: Tan, Yi-Hung Carol, et al.
Publicado: (2017)

ROS1 copy number alterations are frequent in non-small cell lung cancer
por: Clavé, Sergi, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_3utct3kp5f8cifl4246ies50qb