Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients

We report two cases of fatal hepatic failure in patients who received matched unrelated bone marrow transplantation. Both patients presented with high fevers, abnormal liver functions tests, and hypodense lesions in the liver by CT scan. Histologic examination of postmortem liver samples demonstrate...

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Detalles Bibliográficos
Autores principales: Vyas, Jatin M., Marasco, Wayne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426185/
https://www.ncbi.nlm.nih.gov/pubmed/22928129
http://dx.doi.org/10.1155/2012/463569
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author Vyas, Jatin M.
Marasco, Wayne A.
author_facet Vyas, Jatin M.
Marasco, Wayne A.
author_sort Vyas, Jatin M.
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description We report two cases of fatal hepatic failure in patients who received matched unrelated bone marrow transplantation. Both patients presented with high fevers, abnormal liver functions tests, and hypodense lesions in the liver by CT scan. Histologic examination of postmortem liver samples demonstrated extensive necrosis, and immunohistochemistry was positive for adenovirus.
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spelling pubmed-34261852012-08-27 Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients Vyas, Jatin M. Marasco, Wayne A. Case Rep Infect Dis Case Report We report two cases of fatal hepatic failure in patients who received matched unrelated bone marrow transplantation. Both patients presented with high fevers, abnormal liver functions tests, and hypodense lesions in the liver by CT scan. Histologic examination of postmortem liver samples demonstrated extensive necrosis, and immunohistochemistry was positive for adenovirus. Hindawi Publishing Corporation 2012 2012-08-15 /pmc/articles/PMC3426185/ /pubmed/22928129 http://dx.doi.org/10.1155/2012/463569 Text en Copyright © 2012 J. M. Vyas and W. A. Marasco. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Vyas, Jatin M.
Marasco, Wayne A.
Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients
title Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients
title_full Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients
title_fullStr Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients
title_full_unstemmed Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients
title_short Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients
title_sort fatal fulminant hepatic failure from adenovirus in allogeneic bone marrow transplant patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426185/
https://www.ncbi.nlm.nih.gov/pubmed/22928129
http://dx.doi.org/10.1155/2012/463569
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