Quantifying the Diversification of Hepatitis C Virus (HCV) during Primary Infection: Estimates of the In Vivo Mutation Rate

Hepatitis C virus (HCV) is present in the host with multiple variants generated by its error prone RNA-dependent RNA polymerase. Little is known about the initial viral diversification and the viral life cycle processes that influence diversity. We studied the diversification of HCV during acute inf...

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Detalles Bibliográficos
Autores principales: Ribeiro, Ruy M., Li, Hui, Wang, Shuyi, Stoddard, Mark B., Learn, Gerald H., Korber, Bette T., Bhattacharya, Tanmoy, Guedj, Jeremie, Parrish, Erica H., Hahn, Beatrice H., Shaw, George M., Perelson, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426522/
https://www.ncbi.nlm.nih.gov/pubmed/22927817
http://dx.doi.org/10.1371/journal.ppat.1002881

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