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Elucidation of Hepatitis C Virus Transmission and Early Diversification by Single Genome Sequencing

A precise molecular identification of transmitted hepatitis C virus (HCV) genomes could illuminate key aspects of transmission biology, immunopathogenesis and natural history. We used single genome sequencing of 2,922 half or quarter genomes from plasma viral RNA to identify transmitted/founder (T/F...

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Detalles Bibliográficos
Autores principales:	Li, Hui, Stoddard, Mark B., Wang, Shuyi, Blair, Lily M., Giorgi, Elena E., Parrish, Erica H., Learn, Gerald H., Hraber, Peter, Goepfert, Paul A., Saag, Michael S., Denny, Thomas N., Haynes, Barton F., Hahn, Beatrice H., Ribeiro, Ruy M., Perelson, Alan S., Korber, Bette T., Bhattacharya, Tanmoy, Shaw, George M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426529/ https://www.ncbi.nlm.nih.gov/pubmed/22927816 http://dx.doi.org/10.1371/journal.ppat.1002880

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