Cargando…

Secondary Radiation-Induced Bone Tumours Demonstrate a High Degree of Genomic Instability Predictive of a Poor Prognosis

Secondary bone tumours arising in the field of a preceding radiotherapy are a serious late effect, in particular considering the increasing survival times in patients treated for paediatric malignancies. In general, therapy associated tumours are known to show a more aggressive behaviour and a limit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rümenapp, Christine, Smida, Jan, Gonzalez-Vasconcellos, Iria, Baumhoer, Daniel, Malfoy, Bernard, Hadj-Hamou, Nabila-Sandra, Sanli-Bonazzi, Bahar, Nathrath, Michaela, Atkinson, Michael J, Rosemann, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426777/ https://www.ncbi.nlm.nih.gov/pubmed/23450216 http://dx.doi.org/10.2174/138920212802510420

Ejemplares similares

Allelic Imbalances in Radiation—Associated Acute Myeloid Leukemia
por: Klymenko, Sergiy V., et al.
Publicado: (2011)

The long non-coding RNA PARTICLE is associated with WWOX and the absence of FRA16D breakage in osteosarcoma patients
por: O'Leary, Valerie Bríd, et al.
Publicado: (2017)

A Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice
por: Rosemann, Michael, et al.
Publicado: (2014)

How MicroRNA and Transcription Factor Co-regulatory Networks Affect Osteosarcoma Cell Proliferation
por: Poos, Kathrin, et al.
Publicado: (2013)

Structuring osteosarcoma knowledge: an osteosarcoma-gene association database based on literature mining and manual annotation
por: Poos, Kathrin, et al.
Publicado: (2014)

Genomic Heterogeneity of Osteosarcoma - Shift from Single Candidates to Functional Modules
por: Poos, Kathrin, et al.
Publicado: (2015)

Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma – reasons and consequences
por: Arabi, Leila, et al.
Publicado: (2014)

New Small Molecules Targeting Apoptosis and Cell Viability in Osteosarcoma
por: Maugg, Doris, et al.
Publicado: (2015)

CRIP1 expression is correlated with a favorable outcome and less metastases in osteosarcoma patients
por: Baumhoer, Daniel, et al.
Publicado: (2011)

Osteosarcoma cells with genetic signatures of BRCAness are susceptible to the PARP inhibitor talazoparib alone or in combination with chemotherapeutics
por: Engert, Florian, et al.
Publicado: (2016)

The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression
por: Gonzalez-Vasconcellos, I., et al.
Publicado: (2017)

Overactivation of the IGF signalling pathway in osteosarcoma: a potential therapeutic target?
por: Ameline, Baptiste, et al.
Publicado: (2020)

DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma
por: Barenboim, Maxim, et al.
Publicado: (2021)

NTRK fusions in osteosarcoma are rare and non‐functional events
por: Ameline, Baptiste, et al.
Publicado: (2020)

Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells
por: Anastasov, Nataša, et al.
Publicado: (2012)

The immunogenicity of colorectal cancers with high-degree microsatellite instability
por: Banerjea, Ayan, et al.
Publicado: (2005)

Instabilities in hamiltonian systems of two and three degrees of freedom
por: Contopoulos, George
Publicado: (1986)

Quantifying telomeric lncRNAs using PNA-labelled RNA-Flow FISH (RNA-Flow)
por: González-Vasconcellos, Iria, et al.
Publicado: (2022)

Long-term culture of mesenchymal stem cells impairs ATM-dependent recognition of DNA breaks and increases genetic instability
por: Hladik, Daniela, et al.
Publicado: (2019)

The early evolutionary landscape of osteosarcoma provides clues for targeted treatment strategies
por: Kovac, Michal, et al.
Publicado: (2021)

Degree and site of chromosomal instability define its oncogenic potential
por: Hoevenaar, Wilma H. M., et al.
Publicado: (2020)

Methylation and copy number profiling: emerging tools to differentiate osteoblastoma from malignant mimics?
por: Ameline, Baptiste, et al.
Publicado: (2022)

Demonstrating the source of inherent instability in NiFe LDH-based OER electrocatalysts
por: Tyndall, Daire, et al.
Publicado: (2023)

Evolutionary instability of zero-determinant strategies demonstrates that winning is not everything
por: Adami, Christoph, et al.
Publicado: (2013)

Longitudinal Analysis of Image Time Series with Diffeomorphic Deformations: A Computational Framework Based on Stationary Velocity Fields
por: Hadj-Hamou, Mehdi, et al.
Publicado: (2016)

Applying linguistics in the classroom : a sociocultural approach /
por: Razfar, Aria, et al.
Publicado: (2014)

Solitary pulmonary metastases at first recurrence of osteosarcoma: Presentation, treatment, and survival of 219 patients of the Cooperative Osteosarcoma Study Group
por: Mettmann, Vanessa L., et al.
Publicado: (2023)

Control of Intra-Bunch Vertical Instabilities at the SPS - Measurements and Technology Demonstration
por: Fox, John, et al.
Publicado: (2017)

Corrigendum: Evolutionary instability of zero-determinant strategies demonstrates that winning is not everything
por: Adami, Christoph, et al.
Publicado: (2014)

TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome
por: Ribi, Sebastian, et al.
Publicado: (2015)

Assessment of the Speed and Power of Push-Ups Performed on Surfaces with Different Degrees of Instability
por: Marquina Nieto, Moisés, et al.
Publicado: (2022)

Do probiotics promote oral health during orthodontic treatment with fixed appliances? A systematic review
por: Hadj-Hamou, Riham, et al.
Publicado: (2020)

The degree of microsatellite instability predicts response to PD-1 blockade immunotherapy in mismatch repair-deficient/microsatellite instability-high colorectal cancers
por: Wang, Qiao-Xuan, et al.
Publicado: (2021)

DKG-Zertifizierung kinderonkologischer Zentren – ein weites Feld …
por: Lauten, Melchior, et al.
Publicado: (2020)

Association of Radiographic Alignment, Degree of Ankle Instability, Concomitant Pathology, and VAS Pain Scores after the Brostrom-Gould Procedure for Chronic Ankle Instability
por: Ellis, Lauren, et al.
Publicado: (2022)

Common Physical Examination Tests for Patellofemoral Instability Demonstrate Weak Inter-Rater Reliability
por: Hiemstra, Laurie A., et al.
Publicado: (2021)

Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency
por: Kovac, Michal, et al.
Publicado: (2015)

The Advantage of Ambiguity? Enhanced Neural Responses to Multi-Stable Percepts Correlate with the Degree of Perceived Instability
por: Dyson, Benjamin J.
Publicado: (2011)

Stimulation of Epicardial Sympathetic Nerves at Different Sites Induces Cardiac Electrical Instability to Various Degrees
por: Wang, Liang, et al.
Publicado: (2018)

The Synthesis of Associative Copolymers with Both Amphoteric and Hydrophobic Groups and the Effect of the Degree of Association on the Instability of Emulsions
por: Zhang, Xiaotong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b28cl1d7fkn2os69loqn1q4ejk