Treatment-Induced Bone Loss and Fractures in Cancer Patients Undergoing Hormone Ablation Therapy: Efficacy and Safety of Denosumab

Hormone ablation therapy (HALT) for breast or prostate cancer accelerates the development of osteoporosis in both men and women by causing estrogen deficiency, which increases the risk for fracture by promoting bone resorption mediated by osteoclasts. Denosumab, a fully human monoclonal antibody tha...

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Detalles Bibliográficos
Autores principales: Lipton, Allan, Smith, Matthew R., Ellis, Georgiana K., Goessl, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427033/
https://www.ncbi.nlm.nih.gov/pubmed/22933844
http://dx.doi.org/10.4137/CMO.S8511

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