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Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection

BACKGROUND: Living donor liver transplantation (LDLT) is a valuable and legitimate treatment for patients with end-stage liver disease. Computed tomography (CT) has proven to be an important tool in the process of donor evaluation. The purpose of this study was to evaluate the significance of CT in...

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Autores principales: Ringe, Kristina Imeen, Ringe, Bastian Paul, von Falck, Christian, Shin, Hoen-oh, Becker, Thomas, Pfister, Eva-Doreen, Wacker, Frank, Ringe, Burckhardt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427040/
https://www.ncbi.nlm.nih.gov/pubmed/22828359
http://dx.doi.org/10.1186/1471-2342-12-21
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author Ringe, Kristina Imeen
Ringe, Bastian Paul
von Falck, Christian
Shin, Hoen-oh
Becker, Thomas
Pfister, Eva-Doreen
Wacker, Frank
Ringe, Burckhardt
author_facet Ringe, Kristina Imeen
Ringe, Bastian Paul
von Falck, Christian
Shin, Hoen-oh
Becker, Thomas
Pfister, Eva-Doreen
Wacker, Frank
Ringe, Burckhardt
author_sort Ringe, Kristina Imeen
collection PubMed
description BACKGROUND: Living donor liver transplantation (LDLT) is a valuable and legitimate treatment for patients with end-stage liver disease. Computed tomography (CT) has proven to be an important tool in the process of donor evaluation. The purpose of this study was to evaluate the significance of CT in the donor selection process. METHODS: Between May 1999 and October 2010 170 candidate donors underwent biphasic CT. We retrospectively reviewed the results of the CT and liver volumetry, and assessed reasons for rejection. RESULTS: 89 candidates underwent partial liver resection (52.4%). Based on the results of liver CT and volumetry 22 candidates were excluded as donors (31% of the cases). Reasons included fatty liver (n = 9), vascular anatomical variants (n = 4), incidental finding of hemangioma and focal nodular hyperplasia (n = 1) and small (n = 5) or large for size (n = 5) graft volume. CONCLUSION: CT based imaging of the liver in combination with dedicated software plays a key role in the process of evaluation of candidates for LDLT. It may account for up to 1/3 of the contraindications for LDLT.
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spelling pubmed-34270402012-08-25 Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection Ringe, Kristina Imeen Ringe, Bastian Paul von Falck, Christian Shin, Hoen-oh Becker, Thomas Pfister, Eva-Doreen Wacker, Frank Ringe, Burckhardt BMC Med Imaging Research Article BACKGROUND: Living donor liver transplantation (LDLT) is a valuable and legitimate treatment for patients with end-stage liver disease. Computed tomography (CT) has proven to be an important tool in the process of donor evaluation. The purpose of this study was to evaluate the significance of CT in the donor selection process. METHODS: Between May 1999 and October 2010 170 candidate donors underwent biphasic CT. We retrospectively reviewed the results of the CT and liver volumetry, and assessed reasons for rejection. RESULTS: 89 candidates underwent partial liver resection (52.4%). Based on the results of liver CT and volumetry 22 candidates were excluded as donors (31% of the cases). Reasons included fatty liver (n = 9), vascular anatomical variants (n = 4), incidental finding of hemangioma and focal nodular hyperplasia (n = 1) and small (n = 5) or large for size (n = 5) graft volume. CONCLUSION: CT based imaging of the liver in combination with dedicated software plays a key role in the process of evaluation of candidates for LDLT. It may account for up to 1/3 of the contraindications for LDLT. BioMed Central 2012-07-24 /pmc/articles/PMC3427040/ /pubmed/22828359 http://dx.doi.org/10.1186/1471-2342-12-21 Text en Copyright ©2012 Ringe et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ringe, Kristina Imeen
Ringe, Bastian Paul
von Falck, Christian
Shin, Hoen-oh
Becker, Thomas
Pfister, Eva-Doreen
Wacker, Frank
Ringe, Burckhardt
Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title_full Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title_fullStr Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title_full_unstemmed Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title_short Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title_sort evaluation of living liver donors using contrast enhanced multidetector ct – the radiologists impact on donor selection
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427040/
https://www.ncbi.nlm.nih.gov/pubmed/22828359
http://dx.doi.org/10.1186/1471-2342-12-21
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