Comparison of tertiary structures of proteins in protein-protein complexes with unbound forms suggests prevalence of allostery in signalling proteins

BACKGROUND: Most signalling and regulatory proteins participate in transient protein-protein interactions during biological processes. They usually serve as key regulators of various cellular processes and are often stable in both protein-bound and unbound forms. Availability of high-resolution stru...

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Detalles Bibliográficos
Autores principales: Swapna, Lakshmipuram S, Mahajan, Swapnil, de Brevern, Alexandre G, Srinivasan, Narayanaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427047/
https://www.ncbi.nlm.nih.gov/pubmed/22554255
http://dx.doi.org/10.1186/1472-6807-12-6

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