The TT Genotype of the STAT4 rs7574865 Polymorphism Is Associated with High Disease Activity and Disability in Patients with Early Arthritis

BACKGROUND: The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked with an increased risk of developing rheumatoid arthritis. In the present study, we investigated the effects of these genetic vari...

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Detalles Bibliográficos
Autores principales: Lamana, Amalia, Balsa, Alejandro, Rueda, Blanca, Ortiz, Ana M., Nuño, Laura, Miranda-Carus, Maria Eugenia, Gonzalez-Escribano, Maria F., Lopez-Nevot, Miguel A., Pascual-Salcedo, Dora, Martin, Javier, González-Álvaro, Isidoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427144/
https://www.ncbi.nlm.nih.gov/pubmed/22937072
http://dx.doi.org/10.1371/journal.pone.0043661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427144/
https://www.ncbi.nlm.nih.gov/pubmed/22937072
http://dx.doi.org/10.1371/journal.pone.0043661

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