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Mtb-Specific CD27(low) CD4 T Cells as Markers of Lung Tissue Destruction during Pulmonary Tuberculosis in Humans

BACKGROUND: Effector CD4 T cells represent a key component of the host’s anti-tuberculosis immune defense. Successful differentiation and functioning of effector lymphocytes protects the host against severe M. tuberculosis (Mtb) infection. On the other hand, effector T cell differentiation depends o...

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Detalles Bibliográficos
Autores principales: Nikitina, Irina Yu, Kondratuk, Natalya A., Kosmiadi, George A., Amansahedov, Rasul B., Vasilyeva, Irina A., Ganusov, Vitaly V., Lyadova, Irina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427145/
https://www.ncbi.nlm.nih.gov/pubmed/22937086
http://dx.doi.org/10.1371/journal.pone.0043733