Cargando…

Mechanism-Based Urinary Biomarkers to Identify the Potential for Aminoglycoside-Induced Nephrotoxicity in Premature Neonates: A Proof-of-Concept Study

Premature infants are frequently exposed to aminoglycoside antibiotics. Novel urinary biomarkers may provide a non-invasive means for the early identification of aminoglycoside-related proximal tubule renal toxicity, to enable adjustment of treatment and identification of infants at risk of long-ter...

Descripción completa

Detalles Bibliográficos
Autores principales:	McWilliam, Stephen J., Antoine, Daniel J., Sabbisetti, Venkata, Turner, Mark A., Farragher, Tracey, Bonventre, Joseph V., Park, B. Kevin, Smyth, Rosalind L., Pirmohamed, Munir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427159/ https://www.ncbi.nlm.nih.gov/pubmed/22937100 http://dx.doi.org/10.1371/journal.pone.0043809

Ejemplares similares

Aminoglycoside-induced nephrotoxicity in children
por: McWilliam, Stephen J, et al.
Publicado: (2016)

Urinary Biomarkers of Aminoglycoside-Induced Nephrotoxicity in Cystic Fibrosis: Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin
por: McWilliam, Stephen J., et al.
Publicado: (2018)

A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis
por: McWilliam, Stephen J., et al.
Publicado: (2020)

Author Correction: A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis
por: McWilliam, Stephen J., et al.
Publicado: (2020)

Urinary metabolomic markers of aminoglycoside nephrotoxicity in newborn rats
por: Hanna, Mina H, et al.
Publicado: (2013)

2542. Attenuation of Polymyxin and Aminoglycoside-Associated Nephrotoxicity
por: Hudson, Cole, et al.
Publicado: (2023)

Morphological methods to evaluate protective agents against aminoglycoside-induced nephrotoxicity
por: Rodríguez Salgueiro, Sandra, et al.
Publicado: (2015)

Repurposing Statins for Renal Protection: Is It a Class Effect?
por: McWilliam, Stephen J., et al.
Publicado: (2017)

Risk factors for aminoglycoside-associated nephrotoxicity in surgical intensive care unit patients
por: Gerlach, Anthony T, et al.
Publicado: (2011)

The Aging Kidney: Increased Susceptibility to Nephrotoxicity
por: Wang, Xinhui, et al.
Publicado: (2014)

A Proof-of-Concept Investigation of an Energy Management Education Program to Improve Fatigue and Life Participation in Adults on Chronic Dialysis
por: Farragher, Janine F., et al.
Publicado: (2020)

Novel small molecules potentiate premature termination codon readthrough by aminoglycosides
por: Baradaran-Heravi, Alireza, et al.
Publicado: (2016)

High Level Resistance to Aminoglycosides in Urinary Isolates of Enterococci
por: Jyothi, P, et al.
Publicado: (2014)

Enhancing Communication about Paediatric Medicines: Lessons from a Qualitative Study of Parents' Experiences of Their Child's Suspected Adverse Drug Reaction
por: Arnott, Janine, et al.
Publicado: (2012)

Plasma Kidney Injury Molecule-1 in Systemic Lupus Erythematosus: Discordance Between ELISA and Proximity Extension Assay
por: Schmidt, Insa M., et al.
Publicado: (2022)

Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis
por: Grgic, Ivica, et al.
Publicado: (2012)

Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity
por: Wagner, Mark C., et al.
Publicado: (2023)

Development of the Liverpool Adverse Drug Reaction Avoidability Assessment Tool
por: Bracken, Louise E., et al.
Publicado: (2017)

A Novel Agnostic Respiratory Stimulant as a Treatment for Apnea of Prematurity: A Proof-of-Concept Study
por: Miller, Thomas L, et al.
Publicado: (2022)

2348 Lafora disease premature termination codons (PTCs) are likely candidates for suppression by aminoglycosides
por: Simmons, Zoe R., et al.
Publicado: (2018)

Side effects of aminoglycosides on the kidney, ear and balance in cystic fibrosis
por: Prayle, Andrew, et al.
Publicado: (2010)

Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen‐Induced Liver Injury
por: Antoine, Daniel J., et al.
Publicado: (2015)

Variation of Nephrotoxicity Biomarkers by Urinary Storage Condition in Rats
por: Le, Jung-Min, et al.
Publicado: (2014)

ATP/ADP biosensor organoids for drug nephrotoxicity assessment
por: Susa, Koichiro, et al.
Publicado: (2023)

Aminoglycoside-stimulated readthrough of premature termination codons in selected genes involved in primary ciliary dyskinesia
por: Bukowy-Bieryllo, Zuzanna, et al.
Publicado: (2016)

Urinary KIM-1 is not correlated with gestational age among 5-year-old children born prematurely
por: Restrepo, Jaime M., et al.
Publicado: (2023)

Aminoglycosides: Molecular Insights on the Recognition of RNA and Aminoglycoside Mimics
por: Chittapragada, Maruthi, et al.
Publicado: (2009)

The Versatile Transceiver Proof of Concept
por: Troska, J, et al.
Publicado: (2009)

Statin-Related Myotoxicity: A Comprehensive Review of Pharmacokinetic, Pharmacogenomic and Muscle Components
por: Turner, Richard Myles, et al.
Publicado: (2019)

Early detection of acute cisplatin nephrotoxicity: interest of urinary monitoring of proximal tubular biomarkers
por: Bunel, Valérian, et al.
Publicado: (2017)

New Therapeutic Concept of NAD Redox Balance for Cisplatin Nephrotoxicity
por: Oh, Gi-Su, et al.
Publicado: (2016)

The Associations of Plasma Biomarkers of Inflammation With Histopathologic Lesions, Kidney Disease Progression, and Mortality—The Boston Kidney Biopsy Cohort Study
por: Srivastava, Anand, et al.
Publicado: (2021)

Urinary exosomes: a promising biomarker of drug-induced nephrotoxicity
por: Zhou, Zunzhen, et al.
Publicado: (2023)

The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418
por: Ferguson, Michael W., et al.
Publicado: (2019)

A pilot randomised controlled trial to assess the utility of an e‐learning package that trains users in adverse drug reaction causality
por: Conroy, Elizabeth J., et al.
Publicado: (2015)

Feasibility, technique and accuracy of ultrasound-guided transurethral injections into the urinary sphincter of female cadavers: proof of concept
por: Schmid, Florian A., et al.
Publicado: (2020)

Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease
por: Xin, Cuiyan, et al.
Publicado: (2021)

Pharmacogenomics for Primary Care: An Overview
por: Rollinson, Victoria, et al.
Publicado: (2020)

Polygenic risk scores: An overview from bench to bedside for personalised medicine
por: Cross, Benjamin, et al.
Publicado: (2022)

Development and Inter-Rater Reliability of the Liverpool Adverse Drug Reaction Causality Assessment Tool
por: Gallagher, Ruairi M., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_j22ml9v4satmj7m8c62vicf0h7