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Zebrafish foxP2 Zinc Finger Nuclease Mutant Has Normal Axon Pathfinding

foxP2, a forkhead-domain transcription factor, is critical for speech and language development in humans, but its role in the establishment of CNS connectivity is unclear. While in vitro studies have identified axon guidance molecules as targets of foxP2 regulation, and cell culture assays suggest a...

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Detalles Bibliográficos
Autores principales: Xing, Lingyan, Hoshijima, Kazuyuki, Grunwald, David J., Fujimoto, Esther, Quist, Tyler S., Sneddon, Jacob, Chien, Chi-Bin, Stevenson, Tamara J., Bonkowsky, Joshua L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427223/
https://www.ncbi.nlm.nih.gov/pubmed/22937139
http://dx.doi.org/10.1371/journal.pone.0043968