The Protein Kinase KIS Impacts Gene Expression during Development and Fear Conditioning in Adult Mice

The brain-enriched protein kinase KIS (product of the gene UHMK1) has been shown to phosphorylate the human splicing factor SF1 in vitro. This phosphorylation in turn favors the formation of a U2AF(65)-SF1-RNA complex which occurs at the 3′ end of introns at an early stage of spliceosome assembly. H...

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Detalles Bibliográficos
Autores principales: Manceau, Valérie, Kremmer, Elisabeth, Nabel, Elizabeth G., Maucuer, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427225/
https://www.ncbi.nlm.nih.gov/pubmed/22937132
http://dx.doi.org/10.1371/journal.pone.0043946

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