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DNMTs are required for delayed genome instability caused by radiation

The ability of ionizing radiation to initiate genomic instability has been harnessed in the clinic where the localized delivery of controlled doses of radiation is used to induce cell death in tumor cells. Though very effective as a therapy, tumor relapse can occur in vivo and its appearance has bee...

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Detalles Bibliográficos
Autores principales: Armstrong, Christine A., Jones, George D., Anderson, Rhona, Iyer, Pooja, Narayanan, Deepan, Sandhu, Jatinderpal, Singh, Rajinder, Talbot, Christopher J., Tufarelli, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427285/
https://www.ncbi.nlm.nih.gov/pubmed/22722331
http://dx.doi.org/10.4161/epi.21094