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DNMTs are required for delayed genome instability caused by radiation
The ability of ionizing radiation to initiate genomic instability has been harnessed in the clinic where the localized delivery of controlled doses of radiation is used to induce cell death in tumor cells. Though very effective as a therapy, tumor relapse can occur in vivo and its appearance has bee...
Autores principales: | Armstrong, Christine A., Jones, George D., Anderson, Rhona, Iyer, Pooja, Narayanan, Deepan, Sandhu, Jatinderpal, Singh, Rajinder, Talbot, Christopher J., Tufarelli, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427285/ https://www.ncbi.nlm.nih.gov/pubmed/22722331 http://dx.doi.org/10.4161/epi.21094 |
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