Hepatitis C Virus Translation Preferentially Depends on Active RNA Replication

Hepatitis C virus (HCV) RNA initiates its replication on a detergent-resistant membrane structure derived from the endoplasmic reticulum (ER) in the HCV replicon cells. By performing a pulse-chase study of BrU-labeled HCV RNA, we found that the newly-synthesized HCV RNA traveled along the anterograd...

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Detalles Bibliográficos
Autores principales: Liu, Helene Minyi, Aizaki, Hideki, Machida, Keigo, Ou, J.-H. James, Lai, Michael M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427374/
https://www.ncbi.nlm.nih.gov/pubmed/22937067
http://dx.doi.org/10.1371/journal.pone.0043600

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