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A restricted cell population propagates glioblastoma growth following chemotherapy
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, with a median survival of about one year(1). This poor prognosis is due to therapeutic resistance and tumor recurrence following surgical removal. Precisely how recurrence occurs is unknown. Using a genetically-engineere...
Autores principales: | Chen, Jian, Li, Yanjiao, Yu, Tzong-Shiue, McKay, Renée M., Burns, Dennis K., Kernie, Steven G., Parada, Luis F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427400/ https://www.ncbi.nlm.nih.gov/pubmed/22854781 http://dx.doi.org/10.1038/nature11287 |
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