Proapoptotic effects of novel pentabromobenzylisothioureas in human leukemia cell lines

A series of new pentabromobenzylisothioureas [ZKK-1–ZKK-5; (ZKKs)] carrying additional substituents on nitrogen atoms has been synthesized. The ZKKs were found to induce apoptosis in HL-60 (human promyleocytic leukemia) and K-562 (human chronic erythromyeloblastoid leukemia) cell lines in a concentr...

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Detalles Bibliográficos
Autores principales: Koronkiewicz, Mirosława, Chilmonczyk, Zdzisław, Kazimierczuk, Zygmunt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427706/
https://www.ncbi.nlm.nih.gov/pubmed/22942618
http://dx.doi.org/10.1007/s00044-011-9841-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427706/
https://www.ncbi.nlm.nih.gov/pubmed/22942618
http://dx.doi.org/10.1007/s00044-011-9841-8

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