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Proapoptotic effects of novel pentabromobenzylisothioureas in human leukemia cell lines
A series of new pentabromobenzylisothioureas [ZKK-1–ZKK-5; (ZKKs)] carrying additional substituents on nitrogen atoms has been synthesized. The ZKKs were found to induce apoptosis in HL-60 (human promyleocytic leukemia) and K-562 (human chronic erythromyeloblastoid leukemia) cell lines in a concentr...
Autores principales: | Koronkiewicz, Mirosława, Chilmonczyk, Zdzisław, Kazimierczuk, Zygmunt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427706/ https://www.ncbi.nlm.nih.gov/pubmed/22942618 http://dx.doi.org/10.1007/s00044-011-9841-8 |
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