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New Decision Criteria for Selecting Delta Check Methods Based on the Ratio of the Delta Difference to the Width of the Reference Range Can Be Generally Applicable for Each Clinical Chemistry Test Item
BACKGROUND: Many laboratories use 4 delta check methods: delta difference, delta percent change, rate difference, and rate percent change. However, guidelines regarding decision criteria for selecting delta check methods have not yet been provided. We present new decision criteria for selecting delt...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Society for Laboratory Medicine
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427822/ https://www.ncbi.nlm.nih.gov/pubmed/22950070 http://dx.doi.org/10.3343/alm.2012.32.5.345 |
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author | Park, Sang Hyuk Kim, So-Young Lee, Woochang Chun, Sail Min, Won-Ki |
author_facet | Park, Sang Hyuk Kim, So-Young Lee, Woochang Chun, Sail Min, Won-Ki |
author_sort | Park, Sang Hyuk |
collection | PubMed |
description | BACKGROUND: Many laboratories use 4 delta check methods: delta difference, delta percent change, rate difference, and rate percent change. However, guidelines regarding decision criteria for selecting delta check methods have not yet been provided. We present new decision criteria for selecting delta check methods for each clinical chemistry test item. METHODS: We collected 811,920 and 669,750 paired (present and previous) test results for 27 clinical chemistry test items from inpatients and outpatients, respectively. We devised new decision criteria for the selection of delta check methods based on the ratio of the delta difference to the width of the reference range (DD/RR). Delta check methods based on these criteria were compared with those based on the CV% of the absolute delta difference (ADD) as well as those reported in 2 previous studies. RESULTS: The delta check methods suggested by new decision criteria based on the DD/RR ratio corresponded well with those based on the CV% of the ADD except for only 2 items each in inpatients and outpatients. Delta check methods based on the DD/RR ratio also corresponded with those suggested in the 2 previous studies, except for 1 and 7 items in inpatients and outpatients, respectively. CONCLUSIONS: The DD/RR method appears to yield more feasible and intuitive selection criteria and can easily explain changes in the results by reflecting both the biological variation of the test item and the clinical characteristics of patients in each laboratory. We suggest this as a measure to determine delta check methods. |
format | Online Article Text |
id | pubmed-3427822 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Korean Society for Laboratory Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-34278222012-09-05 New Decision Criteria for Selecting Delta Check Methods Based on the Ratio of the Delta Difference to the Width of the Reference Range Can Be Generally Applicable for Each Clinical Chemistry Test Item Park, Sang Hyuk Kim, So-Young Lee, Woochang Chun, Sail Min, Won-Ki Ann Lab Med Original Article BACKGROUND: Many laboratories use 4 delta check methods: delta difference, delta percent change, rate difference, and rate percent change. However, guidelines regarding decision criteria for selecting delta check methods have not yet been provided. We present new decision criteria for selecting delta check methods for each clinical chemistry test item. METHODS: We collected 811,920 and 669,750 paired (present and previous) test results for 27 clinical chemistry test items from inpatients and outpatients, respectively. We devised new decision criteria for the selection of delta check methods based on the ratio of the delta difference to the width of the reference range (DD/RR). Delta check methods based on these criteria were compared with those based on the CV% of the absolute delta difference (ADD) as well as those reported in 2 previous studies. RESULTS: The delta check methods suggested by new decision criteria based on the DD/RR ratio corresponded well with those based on the CV% of the ADD except for only 2 items each in inpatients and outpatients. Delta check methods based on the DD/RR ratio also corresponded with those suggested in the 2 previous studies, except for 1 and 7 items in inpatients and outpatients, respectively. CONCLUSIONS: The DD/RR method appears to yield more feasible and intuitive selection criteria and can easily explain changes in the results by reflecting both the biological variation of the test item and the clinical characteristics of patients in each laboratory. We suggest this as a measure to determine delta check methods. The Korean Society for Laboratory Medicine 2012-09 2012-08-13 /pmc/articles/PMC3427822/ /pubmed/22950070 http://dx.doi.org/10.3343/alm.2012.32.5.345 Text en © The Korean Society for Laboratory Medicine. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Park, Sang Hyuk Kim, So-Young Lee, Woochang Chun, Sail Min, Won-Ki New Decision Criteria for Selecting Delta Check Methods Based on the Ratio of the Delta Difference to the Width of the Reference Range Can Be Generally Applicable for Each Clinical Chemistry Test Item |
title | New Decision Criteria for Selecting Delta Check Methods Based on the Ratio of the Delta Difference to the Width of the Reference Range Can Be Generally Applicable for Each Clinical Chemistry Test Item |
title_full | New Decision Criteria for Selecting Delta Check Methods Based on the Ratio of the Delta Difference to the Width of the Reference Range Can Be Generally Applicable for Each Clinical Chemistry Test Item |
title_fullStr | New Decision Criteria for Selecting Delta Check Methods Based on the Ratio of the Delta Difference to the Width of the Reference Range Can Be Generally Applicable for Each Clinical Chemistry Test Item |
title_full_unstemmed | New Decision Criteria for Selecting Delta Check Methods Based on the Ratio of the Delta Difference to the Width of the Reference Range Can Be Generally Applicable for Each Clinical Chemistry Test Item |
title_short | New Decision Criteria for Selecting Delta Check Methods Based on the Ratio of the Delta Difference to the Width of the Reference Range Can Be Generally Applicable for Each Clinical Chemistry Test Item |
title_sort | new decision criteria for selecting delta check methods based on the ratio of the delta difference to the width of the reference range can be generally applicable for each clinical chemistry test item |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427822/ https://www.ncbi.nlm.nih.gov/pubmed/22950070 http://dx.doi.org/10.3343/alm.2012.32.5.345 |
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