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Prolonged expression of the γ-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment

The normal tissue tolerance levels to fractionated radiotherapy have been appreciated by a century of careful clinical observations and radiobiological studies in animals. During clinical fractionated radiotherapy, these normal tissue tolerance levels are respected, and severe sequelae of radiothera...

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Detalles Bibliográficos
Autores principales: Bourton, Emma C, Plowman, Piers N, Smith, Daniel, Arlett, Colin F, Parris, Christopher N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427882/
https://www.ncbi.nlm.nih.gov/pubmed/21491423
http://dx.doi.org/10.1002/ijc.25953