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Bones' Adaptive Response to Mechanical Loading Is Essentially Linear Between the Low Strains Associated With Disuse and the High Strains Associated With the Lamellar/Woven Bone Transition
There is a widely held view that the relationship between mechanical loading history and adult bone mass/strength includes an adapted state or “lazy zone” where the bone mass/strength remains constant over a wide range of strain magnitudes. Evidence to support this theory is circumstantial. We inves...
Autores principales: | Sugiyama, Toshihiro, Meakin, Lee B, Browne, William J, Galea, Gabriel L, Price, Joanna S, Lanyon, Lance E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427886/ https://www.ncbi.nlm.nih.gov/pubmed/22431329 http://dx.doi.org/10.1002/jbmr.1599 |
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