Autoimmune Dysregulation and Purine Metabolism in Adenosine Deaminase Deficiency

Genetic defects in the adenosine deaminase (ADA) gene are among the most common causes for severe combined immunodeficiency (SCID). ADA-SCID patients suffer from lymphopenia, severely impaired cellular and humoral immunity, failure to thrive, and recurrent infections. Currently available therapeutic...

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Detalles Bibliográficos
Autores principales: Sauer, Aisha Vanessa, Brigida, Immacolata, Carriglio, Nicola, Aiuti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427915/
https://www.ncbi.nlm.nih.gov/pubmed/22969765
http://dx.doi.org/10.3389/fimmu.2012.00265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427915/
https://www.ncbi.nlm.nih.gov/pubmed/22969765
http://dx.doi.org/10.3389/fimmu.2012.00265

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