A novel EGFR-targeted gene delivery system based on complexes self-assembled by EGF, DNA, and activated PAMAM dendrimers

Epidermal growth factor receptor (EGFR)-targeted gene delivery is a promising approach in gene therapy against EGFR-positive cancer. In addition, macromolecules, such as polyamidoamine (PAMAM) dendrimers, are potential nonviral gene carriers in this therapy because of their biocompatibility and modi...

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Detalles Bibliográficos
Autores principales: Yin, Zhe, Liu, Nan, Ma, Mingshu, Wang, Lan, Hao, Yanli, Zhang, Xiaoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428245/
https://www.ncbi.nlm.nih.gov/pubmed/22942644
http://dx.doi.org/10.2147/IJN.S30671

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