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Increasing Coverage of Transcription Factor Position Weight Matrices through Domain-level Homology

Transcription factor-DNA interactions, central to cellular regulation and control, are commonly described by position weight matrices (PWMs). These matrices are frequently used to predict transcription factor binding sites in regulatory regions of DNA to complement and guide further experimental inv...

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Detalles Bibliográficos
Autores principales: Bernard, Brady, Thorsson, Vesteinn, Rovira, Hector, Shmulevich, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428306/
https://www.ncbi.nlm.nih.gov/pubmed/22952610
http://dx.doi.org/10.1371/journal.pone.0042779