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Increasing Coverage of Transcription Factor Position Weight Matrices through Domain-level Homology
Transcription factor-DNA interactions, central to cellular regulation and control, are commonly described by position weight matrices (PWMs). These matrices are frequently used to predict transcription factor binding sites in regulatory regions of DNA to complement and guide further experimental inv...
Autores principales: | Bernard, Brady, Thorsson, Vesteinn, Rovira, Hector, Shmulevich, Ilya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428306/ https://www.ncbi.nlm.nih.gov/pubmed/22952610 http://dx.doi.org/10.1371/journal.pone.0042779 |
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