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Secondhand Smoke Exposure Causes Bronchial Hyperreactivity via Transcriptionally Upregulated Endothelin and 5-hydroxytryptamine 2A Receptors

BACKGROUND: Cigarette smoke exposure is strongly associated with airway hyperreactivity (AHR) which is the main characteristic seen in asthma. The intracellular MAPK signaling pathways are suggested to be associated with the airway damage to the AHR. In the present study, we hypothesize that secondh...

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Detalles Bibliográficos
Autores principales: Cao, Lei, Zhang, Yaping, Cao, Yong-Xiao, Edvinsson, Lars, Xu, Cang-Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428315/
https://www.ncbi.nlm.nih.gov/pubmed/22952915
http://dx.doi.org/10.1371/journal.pone.0044170