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Secondhand Smoke Exposure Causes Bronchial Hyperreactivity via Transcriptionally Upregulated Endothelin and 5-hydroxytryptamine 2A Receptors
BACKGROUND: Cigarette smoke exposure is strongly associated with airway hyperreactivity (AHR) which is the main characteristic seen in asthma. The intracellular MAPK signaling pathways are suggested to be associated with the airway damage to the AHR. In the present study, we hypothesize that secondh...
Autores principales: | Cao, Lei, Zhang, Yaping, Cao, Yong-Xiao, Edvinsson, Lars, Xu, Cang-Bao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428315/ https://www.ncbi.nlm.nih.gov/pubmed/22952915 http://dx.doi.org/10.1371/journal.pone.0044170 |
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