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Primary Human Airway Epithelial Cell-Dependent Inhibition of Human Lung Mast Cell Degranulation
INTRODUCTION: Chronic mast cell activation is a characteristic feature of asthma. BEAS-2B human airway epithelial cells (AEC) profoundly inhibit both constitutive and IgE-dependent human lung mast cell (HLMC) histamine release. The aim of this study was to examine the regulation of HLMC degranulatio...
Autores principales: | Martin, Neil, Ruddick, Andrew, Arthur, Greer K., Wan, Heidi, Woodman, Lucy, Brightling, Christopher E., Jones, Don J. L., Pavord, Ian D., Bradding, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428358/ https://www.ncbi.nlm.nih.gov/pubmed/22970103 http://dx.doi.org/10.1371/journal.pone.0043545 |
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