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Chromatinized Protein Kinase C-θ: Can It Escape the Clutches of NF-κB?

We recently provided the first description of a nuclear mechanism used by Protein Kinase C-theta (PKC-θ) to mediate T cell gene expression. In this mode, PKC-θ tethers to chromatin to form an active nuclear complex by interacting with proteins including RNA polymerase II, the histone kinase MSK-1, t...

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Detalles Bibliográficos
Autores principales:	Sutcliffe, Elissa L., Li, Jasmine, Zafar, Anjum, Hardy, Kristine, Ghildyal, Reena, McCuaig, Robert, Norris, Nicole C., Lim, Pek Siew, Milburn, Peter J., Casarotto, Marco G., Denyer, Gareth, Rao, Sudha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428636/ https://www.ncbi.nlm.nih.gov/pubmed/22969762 http://dx.doi.org/10.3389/fimmu.2012.00260

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