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Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells

BACKGROUND: N-3 polyunsaturated fatty acids, such as docosahexaenoic acid (DHA; 22:6n-3), has clinical significance in the prevention and reversal of nonalcoholic steatohepatitis (NASH). However, the precious mechanism underlying remains unclear. The inflammasome, a multiprotein complex formed by NO...

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Detalles Bibliográficos
Autores principales:	Luo, Xiaoqin, Yang, Yan, Shen, Tianran, Tang, Xilan, Xiao, Yunjun, Zou, Tangbin, Xia, Min, Ling, Wenhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428681/ https://www.ncbi.nlm.nih.gov/pubmed/22515414 http://dx.doi.org/10.1186/1743-7075-9-34

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