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Genetic variants of NOXA and MCL1 modify the risk of HPV16-associated squamous cell carcinoma of the head and neck

ABSTRACTS: BACKGROUND: The cooperation between phorbol 12-myristate 13-acetate induced protein 1 (NOXA) and myeloid cell leukemia 1 (MCL1) is critical in the intrinsic apoptotic pathway. Human papillomavirus 16 (HPV16), by inducing p53 and pRb-E2F degradation, may play an essential role in developme...

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Detalles Bibliográficos
Autores principales:	Zhou, Ziyuan, Sturgis, Erich M, Liu, Zhensheng, Wang, Li-E, Wei, Qingyi, Li, Guojun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428689/ https://www.ncbi.nlm.nih.gov/pubmed/22548841 http://dx.doi.org/10.1186/1471-2407-12-159

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