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1,25-dihydroxyvitamin D(3) inhibits the cytokine-induced secretion of MCP-1 and reduces monocyte recruitment by human preadipocytes

BACKGROUND: Adipose tissue expansion during obesity is associated with a state of low-grade inflammation and an increase in macrophage infiltration, which predisposes to insulin resistance and vascular malfunction. Growing evidence suggests that vitamin D(3) has immunoregulatory effects and adipose...

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Detalles Bibliográficos
Autores principales: Gao, Dan, Trayhurn, Paul, Bing, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428854/
https://www.ncbi.nlm.nih.gov/pubmed/22508334
http://dx.doi.org/10.1038/ijo.2012.53