Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma

Splenic marginal zone lymphoma (SMZL), the most common primary lymphoma of spleen, is poorly understood at the genetic level. In this study, using whole-genome DNA sequencing (WGS) and confirmation by Sanger sequencing, we observed mutations identified in several genes not previously known to be rec...

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Detalles Bibliográficos
Autores principales: Kiel, Mark J., Velusamy, Thirunavukkarasu, Betz, Bryan L., Zhao, Lili, Weigelin, Helmut G., Chiang, Mark Y., Huebner-Chan, David R., Bailey, Nathanael G., Yang, David T., Bhagat, Govind, Miranda, Roberto N., Bahler, David W., Medeiros, L. Jeffrey, Lim, Megan S., Elenitoba-Johnson, Kojo S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428949/
https://www.ncbi.nlm.nih.gov/pubmed/22891276
http://dx.doi.org/10.1084/jem.20120910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428949/
https://www.ncbi.nlm.nih.gov/pubmed/22891276
http://dx.doi.org/10.1084/jem.20120910

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