Pressure overload-induced mild cardiac hypertrophy reduces left ventricular transmural differences in mitochondrial respiratory chain activity and increases oxidative stress

Objective: Increased mechanical stress and contractility characterizes normal left ventricular (LV) subendocardium (Endo) but whether Endo mitochondrial respiratory chain complex activities is reduced as compared to subepicardium (Epi) and whether pressure overload-induced LV hypertrophy (LVH) might...

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Detalles Bibliográficos
Autores principales: Kindo, Michel, Gerelli, Sébastien, Bouitbir, Jamal, Charles, Anne-Laure, Zoll, Joffrey, Hoang Minh, Tam, Monassier, Laurent, Favret, Fabrice, Piquard, François, Geny, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428974/
https://www.ncbi.nlm.nih.gov/pubmed/22934079
http://dx.doi.org/10.3389/fphys.2012.00332

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