Human Pluripotent Stem Cells: Applications and Challenges in Neurological Diseases

The ability to generate human pluripotent stem cells (hPSCs) holds great promise for the understanding and the treatment of human neurological diseases in modern medicine. The hPSCs are considered for their in vitro use as research tools to provide relevant cellular model for human diseases, drug di...

Descripción completa

Detalles Bibliográficos
Autores principales: Hibaoui, Youssef, Feki, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429043/
https://www.ncbi.nlm.nih.gov/pubmed/22934023
http://dx.doi.org/10.3389/fphys.2012.00267
Descripción
Sumario:The ability to generate human pluripotent stem cells (hPSCs) holds great promise for the understanding and the treatment of human neurological diseases in modern medicine. The hPSCs are considered for their in vitro use as research tools to provide relevant cellular model for human diseases, drug discovery, and toxicity assays and for their in vivo use in regenerative medicine applications. In this review, we highlight recent progress, promises, and challenges of hPSC applications in human neurological disease modeling and therapies.

Ejemplares similares