Human Pluripotent Stem Cells: Applications and Challenges in Neurological Diseases

The ability to generate human pluripotent stem cells (hPSCs) holds great promise for the understanding and the treatment of human neurological diseases in modern medicine. The hPSCs are considered for their in vitro use as research tools to provide relevant cellular model for human diseases, drug di...

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Detalles Bibliográficos
Autores principales: Hibaoui, Youssef, Feki, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429043/
https://www.ncbi.nlm.nih.gov/pubmed/22934023
http://dx.doi.org/10.3389/fphys.2012.00267
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author Hibaoui, Youssef
Feki, Anis
author_facet Hibaoui, Youssef
Feki, Anis
author_sort Hibaoui, Youssef
collection PubMed
description The ability to generate human pluripotent stem cells (hPSCs) holds great promise for the understanding and the treatment of human neurological diseases in modern medicine. The hPSCs are considered for their in vitro use as research tools to provide relevant cellular model for human diseases, drug discovery, and toxicity assays and for their in vivo use in regenerative medicine applications. In this review, we highlight recent progress, promises, and challenges of hPSC applications in human neurological disease modeling and therapies.
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spelling pubmed-34290432012-08-29 Human Pluripotent Stem Cells: Applications and Challenges in Neurological Diseases Hibaoui, Youssef Feki, Anis Front Physiol Physiology The ability to generate human pluripotent stem cells (hPSCs) holds great promise for the understanding and the treatment of human neurological diseases in modern medicine. The hPSCs are considered for their in vitro use as research tools to provide relevant cellular model for human diseases, drug discovery, and toxicity assays and for their in vivo use in regenerative medicine applications. In this review, we highlight recent progress, promises, and challenges of hPSC applications in human neurological disease modeling and therapies. Frontiers Research Foundation 2012-07-20 /pmc/articles/PMC3429043/ /pubmed/22934023 http://dx.doi.org/10.3389/fphys.2012.00267 Text en Copyright © 2012 Hibaoui and Feki. http://www.frontiersin.org/licenseagreement This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Physiology
Hibaoui, Youssef
Feki, Anis
Human Pluripotent Stem Cells: Applications and Challenges in Neurological Diseases
title Human Pluripotent Stem Cells: Applications and Challenges in Neurological Diseases
title_full Human Pluripotent Stem Cells: Applications and Challenges in Neurological Diseases
title_fullStr Human Pluripotent Stem Cells: Applications and Challenges in Neurological Diseases
title_full_unstemmed Human Pluripotent Stem Cells: Applications and Challenges in Neurological Diseases
title_short Human Pluripotent Stem Cells: Applications and Challenges in Neurological Diseases
title_sort human pluripotent stem cells: applications and challenges in neurological diseases
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429043/
https://www.ncbi.nlm.nih.gov/pubmed/22934023
http://dx.doi.org/10.3389/fphys.2012.00267
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