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Omega 3 fatty acid inhibition of inflammatory cytokine-mediated Connexin43 regulation in the heart

Background: The proinflammatory cytokine Interleukin-1β (IL-1β), which increases in the heart post myocardial infarction (MI), has been shown to cause loss of Connexin43 (Cx43) function, an event known to underlie formation of the arrhythmogenic substrate. Omega 3 Fatty acids exhibit antiarrhythmic...

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Detalles Bibliográficos
Autores principales: Baum, Jennifer R., Dolmatova, Elena, Tan, Alex, Duffy, Heather S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429046/
https://www.ncbi.nlm.nih.gov/pubmed/22934026
http://dx.doi.org/10.3389/fphys.2012.00272