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Understanding complexity in neurodegenerative diseases: in silico reconstruction of emergence

Healthy functioning is an emergent property of the network of interacting biomolecules that comprise an organism. It follows that disease (a network shift that causes malfunction) is also an emergent property, emerging from a perturbation of the network. On the one hand, the biomolecular network of...

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Detalles Bibliográficos
Autores principales: Kolodkin, Alexey, Simeonidis, Evangelos, Balling, Rudi, Westerhoff, Hans V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429063/
https://www.ncbi.nlm.nih.gov/pubmed/22934043
http://dx.doi.org/10.3389/fphys.2012.00291