Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes: An Individual Patient Data Meta-analysis of 9,153 Patients

BACKGROUND: Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used to treat MDR-TB. METHODS AND FINDIN...

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Detalles Bibliográficos
Autores principales: Ahuja, Shama D., Ashkin, David, Avendano, Monika, Banerjee, Rita, Bauer, Melissa, Bayona, Jamie N., Becerra, Mercedes C., Benedetti, Andrea, Burgos, Marcos, Centis, Rosella, Chan, Eward D., Chiang, Chen-Yuan, Cox, Helen, D'Ambrosio, Lia, DeRiemer, Kathy, Dung, Nguyen Huy, Enarson, Donald, Falzon, Dennis, Flanagan, Katherine, Flood, Jennifer, Garcia-Garcia, Maria L., Gandhi, Neel, Granich, Reuben M., Hollm-Delgado, Maria G., Holtz, Timothy H., Iseman, Michael D., Jarlsberg, Leah G., Keshavjee, Salmaan, Kim, Hye-Ryoun, Koh, Won-Jung, Lancaster, Joey, Lange, Christophe, de Lange, Wiel C. M., Leimane, Vaira, Leung, Chi Chiu, Li, Jiehui, Menzies, Dick, Migliori, Giovanni B., Mishustin, Sergey P., Mitnick, Carole D., Narita, Masa, O'Riordan, Philly, Pai, Madhukar, Palmero, Domingo, Park, Seung-kyu, Pasvol, Geoffrey, Peña, Jose, Pérez-Guzmán, Carlos, Quelapio, Maria I. D., Ponce-de-Leon, Alfredo, Riekstina, Vija, Robert, Jerome, Royce, Sarah, Schaaf, H. Simon, Seung, Kwonjune J., Shah, Lena, Shim, Tae Sun, Shin, Sonya S., Shiraishi, Yuji, Sifuentes-Osornio, José, Sotgiu, Giovanni, Strand, Matthew J., Tabarsi, Payam, Tupasi, Thelma E., van Altena, Robert, Van der Walt, Martie, Van der Werf, Tjip S., Vargas, Mario H., Viiklepp, Pirett, Westenhouse, Janice, Yew, Wing Wai, Yim, Jae-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429397/
https://www.ncbi.nlm.nih.gov/pubmed/22952439
http://dx.doi.org/10.1371/journal.pmed.1001300

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