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Increased Responsiveness of Peripheral Blood Mononuclear Cells to In Vitro TLR 2, 4 and 7 Ligand Stimulation in Chronic Pain Patients
Glial activation via Toll-like receptor (TLR) signaling has been shown in animals to play an important role in the initiation and establishment of chronic pain. However, our ability to assess this central immune reactivity in clinical pain populations is currently lacking. Peripheral blood mononucle...
Autores principales: | Kwok, Yuen H., Hutchinson, Mark R., Gentgall, Melanie G., Rolan, Paul E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429430/ https://www.ncbi.nlm.nih.gov/pubmed/22937165 http://dx.doi.org/10.1371/journal.pone.0044232 |
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