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Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials
AIMS: To assess parental attitudes towards type 1 diabetes clinical trials (T1DCTs) and factors that impact willingness to enroll their children with and without diabetes. METHODS: A cross-sectional survey of parents of children with type 1 diabetes was administered at an academic clinic and a diabe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429434/ https://www.ncbi.nlm.nih.gov/pubmed/22937171 http://dx.doi.org/10.1371/journal.pone.0044341 |
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author | Buscariollo, Daniela L. Davidson, Mario A. Black, Margo Russell, William E. Rothman, Russell L. Moore, Daniel J. |
author_facet | Buscariollo, Daniela L. Davidson, Mario A. Black, Margo Russell, William E. Rothman, Russell L. Moore, Daniel J. |
author_sort | Buscariollo, Daniela L. |
collection | PubMed |
description | AIMS: To assess parental attitudes towards type 1 diabetes clinical trials (T1DCTs) and factors that impact willingness to enroll their children with and without diabetes. METHODS: A cross-sectional survey of parents of children with type 1 diabetes was administered at an academic clinic and a diabetes educational event. RESULTS: Survey response rate was 36%. Of 166 participating parents, 76% were aware of T1DCTs. More parents reported willingness to enroll children with diabetes (47%) than unaffected children (36%). Only 18% recalled being asked to enroll their children, and of these, 60% agreed to enroll at least some of those times. Less than 30% were comfortable with placebos. Factors predicting willingness to enroll children with diabetes included healthcare provider trust, comfort with consent by proxy, low fear of child being a “guinea pig,” and comfort with placebo. Factors predicting willingness to enroll unaffected children were provider trust, comfort with consent by proxy, comfort with placebo, and perceived ease of understanding T1DCT information. CONCLUSIONS: Parents report moderate willingness to enroll children in T1DCTs. Willingness is diminished by common trial methodologies. Although most parents recalled receiving trial-related information, significantly fewer recalled being asked to participate. Efforts to optimize effective communication around identified areas of parental concern may increase T1DCT participation. |
format | Online Article Text |
id | pubmed-3429434 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-34294342012-08-30 Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials Buscariollo, Daniela L. Davidson, Mario A. Black, Margo Russell, William E. Rothman, Russell L. Moore, Daniel J. PLoS One Research Article AIMS: To assess parental attitudes towards type 1 diabetes clinical trials (T1DCTs) and factors that impact willingness to enroll their children with and without diabetes. METHODS: A cross-sectional survey of parents of children with type 1 diabetes was administered at an academic clinic and a diabetes educational event. RESULTS: Survey response rate was 36%. Of 166 participating parents, 76% were aware of T1DCTs. More parents reported willingness to enroll children with diabetes (47%) than unaffected children (36%). Only 18% recalled being asked to enroll their children, and of these, 60% agreed to enroll at least some of those times. Less than 30% were comfortable with placebos. Factors predicting willingness to enroll children with diabetes included healthcare provider trust, comfort with consent by proxy, low fear of child being a “guinea pig,” and comfort with placebo. Factors predicting willingness to enroll unaffected children were provider trust, comfort with consent by proxy, comfort with placebo, and perceived ease of understanding T1DCT information. CONCLUSIONS: Parents report moderate willingness to enroll children in T1DCTs. Willingness is diminished by common trial methodologies. Although most parents recalled receiving trial-related information, significantly fewer recalled being asked to participate. Efforts to optimize effective communication around identified areas of parental concern may increase T1DCT participation. Public Library of Science 2012-08-28 /pmc/articles/PMC3429434/ /pubmed/22937171 http://dx.doi.org/10.1371/journal.pone.0044341 Text en © 2012 Buscariollo et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Buscariollo, Daniela L. Davidson, Mario A. Black, Margo Russell, William E. Rothman, Russell L. Moore, Daniel J. Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials |
title | Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials |
title_full | Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials |
title_fullStr | Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials |
title_full_unstemmed | Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials |
title_short | Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials |
title_sort | factors that influence parental attitudes toward enrollment in type 1 diabetes trials |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429434/ https://www.ncbi.nlm.nih.gov/pubmed/22937171 http://dx.doi.org/10.1371/journal.pone.0044341 |
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