Gene Silencing of FANCF Potentiates the Sensitivity to Mitoxantrone through Activation of JNK and p38 Signal Pathways in Breast Cancer Cells

Fanconi anemia complementation group-F (FANCF) is a key factor to maintain the function of FA/BRCA, a DNA-damage response pathway. However, the functional role of FANCF in breast cancer has not been elucidated. In this study, we examined the effects and mechanisms of FANCF-RNAi on the sensitivity of...

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Detalles Bibliográficos
Autores principales: Li, Yanlin, Zhao, Lin, Sun, Haigang, Yu, Jiankun, Li, Na, Liang, Jingwei, Wang, Yan, He, Miao, Bai, Xuefeng, Yu, Zhaojin, Zheng, Zhihong, Mi, Xiaoyi, Wang, Enhua, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429446/
https://www.ncbi.nlm.nih.gov/pubmed/22952942
http://dx.doi.org/10.1371/journal.pone.0044254

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