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Transcriptional Regulation of Mouse PXR Gene: An Interplay of Transregulatory Factors
Pregnane X Receptor (PXR) is an important ligand-activated nuclear receptor functioning as a ‘master regulator’ of expression of phase I, phase II drug metabolizing enzymes, and members of the drug transporters. PXR is primarily expressed in hepatic tissues and to lesser extent in other non-hepatic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429448/ https://www.ncbi.nlm.nih.gov/pubmed/22952895 http://dx.doi.org/10.1371/journal.pone.0044126 |