Cargando…

AAV-Mediated Knock-Down of HRC Exacerbates Transverse Aorta Constriction-Induced Heart Failure

BACKGROUND: Histidine-rich calcium binding protein (HRC) is located in the lumen of sarcoplasmic reticulum (SR) that binds to both triadin (TRN) and SERCA affecting Ca(2+) cycling in the SR. Chronic overexpression of HRC that may disrupt intracellular Ca(2+) homeostasis is implicated in pathogenesis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Chang Sik, Cha, Hyeseon, Kwon, Eun Jeong, Jeong, Dongtak, Hajjar, Roger J., Kranias, Evangelia G., Cho, Chunghee, Park, Woo Jin, Kim, Do Han
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429470/ https://www.ncbi.nlm.nih.gov/pubmed/22952658 http://dx.doi.org/10.1371/journal.pone.0043282

Ejemplares similares

Effects of Adiponectin on Diastolic Function in Mice Underwent Transverse Aorta Constriction
por: Han, Xueting, et al.
Publicado: (2019)

Characterization of Transverse Aortic Constriction in Mice Based on the Specific Recruitment of Leukocytes to the Hypertrophic Myocardium and the Aorta Ascendens
por: Kleiner, Jan Lukas, et al.
Publicado: (2021)

Helicobacter pylori Stress-Response: Definition of the HrcA Regulon
por: Roncarati, Davide, et al.
Publicado: (2019)

The Role of Early Diagnosis of Hepatorenal Cystic (HRC) Syndrome in Children-Clinical Trial
por: MATEESCU, DIANA ŞTEFANIA, et al.
Publicado: (2017)

Rapid conditional knock-down–knock-in system for mammalian cells
por: Hölzel, Michael, et al.
Publicado: (2007)

The effect of SIRT1 protein knock down on PGC-1α acetylation during skeletal muscle contraction
por: Park, Dae Ryoung, et al.
Publicado: (2014)

In vivo knock-down of multidrug resistance transporters ABCC1 and ABCC2 by AAV-delivered shRNAs and by artificial miRNAs
por: Borel, Florie, et al.
Publicado: (2011)

Constriction of juxta-ductal aorta and rapid progression of obstruction in a newborn
por: Awasthy, Neeraj, et al.
Publicado: (2010)

Cooperative Regulation of Campylobacter jejuni Heat-Shock Genes by HspR and HrcA
por: Palombo, Marta, et al.
Publicado: (2020)

Identification of a GrgA-Euo-HrcA Transcriptional Regulatory Network in Chlamydia
por: Wurihan, Wurihan, et al.
Publicado: (2021)

Feeling the Heat: The Campylobacter jejuni HrcA Transcriptional Repressor Is an Intrinsic Protein Thermosensor
por: Versace, Giovanni, et al.
Publicado: (2021)

HRC promotes anoikis resistance and metastasis by suppressing endoplasmic reticulum stress in hepatocellular carcinoma
por: Xia, Suhong, et al.
Publicado: (2021)

Loss of OsHRC function confers blast resistance without yield penalty in rice
por: Ding, Yanpeng, et al.
Publicado: (2023)

Fumonisin B1-Induced Toxicity Was Not Exacerbated in Glutathione Peroxidase-1/Catalase Double Knock Out Mice
por: Yayeh, Taddesse, et al.
Publicado: (2021)

Knocked down a Notch with age
por: LeBrasseur, Nicole
Publicado: (2003)

Knocking down Disease with siRNAs
por: Dykxhoorn, Derek M., et al.
Publicado: (2006)

Enhancing atrial‐specific gene expression using a calsequestrin cis‐regulatory module 4 with a sarcolipin promoter
por: Yoo, Jimeen, et al.
Publicado: (2018)

Hdac8 Inhibitor Alleviates Transverse Aortic Constriction-Induced Heart Failure in Mice by Downregulating Ace1
por: Zhao, Tingwei, et al.
Publicado: (2022)

Chemical Methods to Knock Down the Amyloid Proteins
por: Gao, Na, et al.
Publicado: (2017)

Apoptotic-like PCD inducing HRC gene when silenced enhances multiple disease resistance in plants
por: Kushalappa, A. C., et al.
Publicado: (2022)

Distinct Phenotypes Induced by Three Degrees of Transverse Aortic Constriction in Mice
por: Richards, Daniel A., et al.
Publicado: (2019)

CRISPR/Cas9-AAV Mediated Knock-in at NRL Locus in Human Embryonic Stem Cells
por: Ge, Xianglian, et al.
Publicado: (2016)

40008 COMBINED CRISPR/CAS9 AND AAV FOR THE GENERATION OF CONDITIONAL ISOGENIC GENE KNOCK-INS
por: Boddu, Prajwal, et al.
Publicado: (2021)

HrcQ Provides a Docking Site for Early and Late Type III Secretion Substrates from Xanthomonas
por: Lorenz, Christian, et al.
Publicado: (2012)

The histidine-rich calcium binding protein (HRC) promotes tumor metastasis in hepatocellular carcinoma and is upregulated by SATB1
por: Liu, Jingmei, et al.
Publicado: (2015)

PB2023: UPDATE AND FOLLOW-UP OF NEWLY DIAGNOSED MULTIPLE MYELOMA (NDMM) WITH HIGH-RISK CYTOGENETIC (HRC).
por: Nuevo López, M. I., et al.
Publicado: (2022)

Anti-angiogenesis in prostate cancer: knocked down but not out
por: Bilusic, Marijo, et al.
Publicado: (2014)

Knocking down the obstacles to functional genomics data sharing
por: Simpson, Kaylene J., et al.
Publicado: (2017)

Knocking down barriers: advances in siRNA delivery
por: Whitehead, Kathryn A., et al.
Publicado: (2009)

A diastolic dysfunction model in non-human primates with transverse aortic constriction
por: ZHEN, Nicole, et al.
Publicado: (2021)

Identification of Ferroptosis-Related Genes in Heart Failure Induced by Transverse Aortic Constriction
por: Gu, Jian Jun, et al.
Publicado: (2023)

A Case of Aneurysm of the Transverse Part of the Arch of Aorta
por: Sen, A. R.
Publicado: (1943)

SUMO1-dependent modulation of SERCA2a in heart failure
por: Kho, Changwon, et al.
Publicado: (2011)

Structure-Function Analysis of the HrpB2-HrcU Interaction in the Xanthomonas citri Type III Secretion System
por: Cappelletti, Paola A., et al.
Publicado: (2011)

Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells
por: Liu, Jingmei, et al.
Publicado: (2016)

Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease
por: Baker, Emily, et al.
Publicado: (2019)

Biophysical characterization of HRC peptide analogs interaction with heptad repeat regions of the SARS-coronavirus Spike fusion protein core
por: Yan, Zhe, et al.
Publicado: (2006)

Protocols for marker-free gene knock-out and knock-down in Kluyveromyces marxianus using CRISPR/Cas9
por: Rajkumar, Arun S, et al.
Publicado: (2021)

Gene amplification in human cells knocked down for RAD54
por: Ruiz-Herrera, Aurora, et al.
Publicado: (2011)

Effect of Knocking Down the Insulin Receptor on Mouse Rod Responses
por: Woodruff, Michael L., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_sen2ptb5u9aia4d9u5ibhbm4im