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Itga2b Regulation at the Onset of Definitive Hematopoiesis and Commitment to Differentiation
Product of the Itga2b gene, CD41 contributes to hematopoietic stem cell (HSC) and megakaryocyte/platelet functions. CD41 expression marks the onset of definitive hematopoiesis in the embryo where it participates in regulating the numbers of multipotential progenitors. Key to platelet aggregation, CD...
Autores principales: | Dumon, Stephanie, Walton, David S., Volpe, Giacomo, Wilson, Nicola, Dassé, Emilie, Pozzo, Walter Del, Landry, Josette-Renee, Turner, Bryan, O’Neill, Laura P., Göttgens, Berthold, Frampton, Jon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429474/ https://www.ncbi.nlm.nih.gov/pubmed/22952660 http://dx.doi.org/10.1371/journal.pone.0043300 |
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